Author(s): Lida Ameli Kalkhoran, Majid Mirmohammadkhani, Sajjad Rahimi Pordanjani, Soodeh Hooshmandi* and Hamed Abbasizadeghoroghchi
Objective: The aim of this study was to compare echocardiographic findings in neonates born to mothers with COVID-19 and neonates born to healthy mothers referred to Amir Al-Momenin Hospital of Semnan in 2021.
Methods: This case-control study was conducted on 60 neonates born to mothers with COVID-19 (case group; n=30) and neonates born to healthy mothers (control group; n=30) referred to Amir Al-Momenin Hospital of Semnan in 2021. The sampling method was random and the data collection tool was a checklist including sex, birth weight, gestational age, heart rate, mitral valve E wave, mitral valve A wave, TAPSE and LVEF. The evaluation of echocardiographic parameters performed using Philips Affinity 50 Ultrasound Machine. Finally, data analysis was applied by SPSS 24 at 5% significant level.
Results: There was no statistically significant difference between the two groups in terms of birth weight, gestational age, heart rate, mitral valve E wave, mitral valve a wave, left ventricular function, TAPSE and LVEF. In addition, the means TAPSE and LVEF according to sex were not significant in the two groups. We observed a significant Positive correlation between gestational age with TAPSE and LVEF in the two groups, however, the correlation between the left ventricular function and gestational age was negative in newborns of infected mothers. Also, a significant positive correlation between birth weight with TAPSE and LVEF in the two groups.
Conclusion: This study showed the echocardiographic findings in neonates born to mothers with COVID-19 and neonates born to healthy mothers were not significantly different, however, cohort studies with higher sample size are recommended.
